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Take subway to South Station. Exit left of Rail Tracks from main terminal. Follow Summer St. across Ft. Point bridge.  Take your first right at Melcher St  which dead ends at A St.

 319 A Street is to the left of the P.O. Parking Lot.  Walk around left side of the building  to the REAR building on right.  There is a green door with stairs going to the 5th FL.